Nonclinical Manager - Translational Pharmacology

JOB DESCRIPTION

Department: Translational pharmacology

Reports to: Senior director translational pharmacology

Location: London

MAIN PURPOSE OF JOB                                                                                                                         

As the nonclinical manager you will be a pivotal member of the Research and Translational Medicine team at Evox.  You will play a key role in delivering preclinical studies for the characterisation of Evox’s platforms and pharmacology of this new class of therapeutics in rare disease programmes, advancing Evox’s therapeutic pipeline.

KEY ACCOUNTABILITIES

• Responsible for the management of Evox’s vivarium and collaboration with facility’s team, arranging for technical support as needed
• Lead planning and execution of preclinical studies in collaboration with translational medicine, research, and CMC
• Ensuring delivery of high-quality data and completion of studies on time and within budget
• Liaising with partners and collaborators to ensure study samples are stored, shared and analysed appropriately
• Responsible for compliance and maintaining rigorous standards
• Role model the Company values and leadership behaviours, cultivating high performing and highly engaged teams
• Build strong working relationships with enabling functions, including Finance and Facilities

PERSON SPECIFICATION

It is expected the candidate will have significant experience of managing preclinical studies including design, execution, and reporting.  They will be experienced across a variety of techniques and have a track record of demonstrating high ethical and welfare standards.  The candidate must have strong inter-personal skills and be confident in leading studies and communicating with the colleagues across disciplines.  They will be delivery focussed and comfortable working in an agile and team-oriented environment.

Experience & knowledge

• A minimum of 10 years' experience working in a vivarium and leading preclinical research activities
• A personal Home Office Licence (EU modules 1-8, 20-22; or UK Pil A, B, C)
• Good knowledge of the drug discovery process
• Industry experience, particularly in a regulatory environment is highly desirable
• Experience of working with new drug modalities or advanced biological approaches particularly experience working with RNA or AAV genetic therapies is preferred
• An entrepreneurial attitude and able to work in a fast-paced and agile environment; self-motivated with a high level of attention to detail whilst keeping objectives in sight
• Excellent communication & interpersonal skills with experience analysing, interpreting, and presenting complex scientific data, whilst appropriately targeting audiences

KEY BEHAVIOURAL ATTRIBUTES – ALL STAFF

People with Purpose – We are innovative and creative in the way we work and deliver. We treat each other with respect and dignity and work collaboratively to learn from each other’s strengths.

Driven to Deliver – We strive to deliver our objectives, and then look for our next challenge. We recognise our achievements and celebrate our successes.

Agile and Accountable – We respond to challenges impacting our progress and find creative and innovative solutions to overcome obstacles. We are brave and not afraid to change our approach to achieve a positive outcome in optimum time.

Candid and Constructive – We communicate with honesty and transparency throughout the team.  We value giving and receiving constructive feedback to each other and our partners.