Study Director - Translational Pharmacology

JOB DESCRIPTION

Department: Translational pharmacology

Reports to: Senior director translational pharmacology

Location: Oxford

MAIN PURPOSE OF JOB                                                                                                                         

As a Study Director in Translational Pharmacology, you will be a pivotal member of the Research and Translational Medicine team at Evox.  You will play a key role in operational management and design of preclinical studies for the characterisation of Evox’s platforms and therapeutic pipeline in rare diseases.  You will be particularly focussed in ensuring the smooth delivery of high quality data for preclinical regulatory studies.

KEY ACCOUNTABILITIES 

• Responsible for operational delivery of Evox’s preclinical portfolio, working across departments and with collaborators and outsourcing partners
• Lead planning, coordination and delivery of external work packages, including breeding programmes, scheduling studies and supply of study materials
• Designing studies and reviewing study plans and study reports to ensure robust study design and delivery of high quality data
• Liaising with project management and cmc for ensuring material to support studies
• Act as the key point of contact for external studies
• Responsible for compliance and maintaining rigorous standards

• Role model the Company values and leadership behaviours, cultivating high performing and highly engaged teams
• Build strong working relationships with enabling functions, including Finance and Facilities

PERSON SPECIFICATION

It is expected the candidate will have significant experience of preclinical PK/PD and toxicology studies, including both hands on and project management activities.  They will be experienced in delivering preclinical studies and have a breadth of knowledge across preclinical regulatory studies.  The candidate must have experience of outsourcing management and the ability to build strong relationships with colleagues and external partners.  They should be highly organised, possess good attention to detail and communicate effectively across multi discipline teams.  They will be delivery focussed and comfortable working in an agile and team-oriented environment.

Experience & knowledge

• PhD in a relevant subject and minimum of 10 years' experience designing and leading preclinical studies, preferably from a DMPK or GLP toxicology background
• Experience of managing reports and compiling data across a variety of activities such as in life findings, pathology, clinical biochemistry and safety pharmacology
• Track record of managing projects including outsourcing and working with external partners
• Directing studies with non-standard designs
• Good knowledge of the drug discovery process, preferably from an industry setting
• Experience of working with new drug modalities or advanced biological approaches particularly experience working with RNA or AAV genetic therapies is preferred
• An entrepreneurial attitude and able to work in a fast-paced and agile environment; self-motivated with a high level of attention to detail whilst keeping objectives in sight
• Excellent communication & interpersonal skills with experience analysing, interpreting, and presenting complex scientific data, whilst appropriately targeting audiences

KEY BEHAVIOURAL ATTRIBUTES – ALL STAFF

People with Purpose – We are innovative and creative in the way we work and deliver. We treat each other with respect and dignity and work collaboratively to learn from each other’s strengths.

Driven to Deliver – We strive to deliver our objectives, and then look for our next challenge. We recognise our achievements and celebrate our successes.

Agile and Accountable – We respond to challenges impacting our progress and find creative and innovative solutions to overcome obstacles. We are brave and not afraid to change our approach to achieve a positive outcome in optimum time.

Candid and Constructive – We communicate with honesty and transparency throughout the team.  We value giving and receiving constructive feedback to each other and our partners.